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Laboratory Members
A/Prof Duncan (Jock) Campbell
Senior Research Fellow
Molecular Cardiology Unit
St Vincent's Institute
Telephone: +61 3 9288 2501
Facsimile: +61 3 9416 2676
Email: dcampbell@svi.edu.au
Other Position:
- Senior Research Fellow, St. Vincent's Institute of Medical Research
- Associate Professor and Principal Fellow (Honorary), University of Melbourne, Department of Medicine, St. Vincent's Hospital, Victoria, Australia
- Clinical Assistant (Honorary), Hypertension Clinic, St. Vincent's Hospital, Victoria, Australia
Education:
| 1973 | B.Med.Sc. University of Melbourne, Victoria, Australia |
| 1973 | MB.BS. University of Melbourne, Victoria, Australia |
| 1980 | Fellow Royal Australasian College of Physicians |
| 1997 | Grad.Dip.Epid.Biostat. University of Melbourne, Victoria, Australia |
| 2005 | Fellow Cardiac Society of Australia and New Zealand |
Awards:
| 1968 | National Heart Foundation of Australia Scholarship |
| 1970 | National Heart Foundation of Australia Vacation Scholarship |
| 1979-1981 | NH&MRC Medical Postgraduate Research Award |
| 1982 | Royal Australasian College of Physicians Bushell Travelling Fellowship in Medicine or the Allied Sciences |
| 1982 | Postdoctoral Research Fellowship from the Institut National de la Sante et de la Recherche Medicale (INSERM), France |
| 1983-1985, 1986-1987 | NH&MRC C. J. Martin Fellowship |
| 1985-1986 | International Research Fellowship, from the Fogarty International Centre, National Institutes of Health, USA |
| 1986 | Demuth Young Investigator Award of the International Society of Hypertension |
Scientific Involvement:
| Society membership | |
| 1970 | Member, Australian Society for Experimental Pathology |
| 1974-present | Member, Australian Medical Association |
| 1978-present | Member, The Australian Society for Medical Research |
| 1978-present | Member, Endocrine Society of Australia |
| 1980-present | Fellow, Royal Australasian College of Physicians |
| 1986-2004 | Member, The Endocrine Society (USA) |
| 1988-present | Member, International Society of Hypertension |
| 1991-present | Member, National Association of Research Fellows |
| 2004 | Member, Cardiac Society of Australia and New Zealand |
| 2005 | Fellow, Cardiac Society of Australia and New Zealand |
| Committee memberships - Internal | |
| 1996-2002 | Member, Scientific Secretariat, Human Research Ethics Committee, St. Vincent's Hospital, Victoria, Australia |
| 1998 | Editor, Annual Report, St. Vincent's Institute of Medical Research |
| 1999-2002 | Member, Ph.D. Committee, University of Melbourne, Department of Medicine, St. Vincent's Hospital, Victoria, Australia |
| Committee memberships - External | |
| 2004-present | Member, NHF Heart Failure Guidelines Committee |
| Conference organization | |
| 1993-1994 | Member, program committee, 15th Scientific Meeting of the International Society of Hypertension |
| 1993-1994 | Member, local organising committee, Kallikreins &Kinins & Cardiovascular Function, Satellite to the 15th Scientific Meeting of the International Society of Hypertension |
| 1999-2001 | Member, local organising committee, Renin Angiotensin System, Satellite to IUPS 2001 |
| 2003-2004 | Co-Chair, Third International Symposium on AMP-activated protein kinase. |
| Editorial | |
| 1991-1993 | Member, Editorial Board, Journal of Hypertension |
| 1992-2001 | Member, Editorial Board, Hypertension |
Research Interests:
Cardiovascular disease, hypertension, cardiac failure, renin-angiotensin system, kallikrein kinin system, natriuretic peptides
Representative publications from a total of 87 original papers, 17 reviews, and 8 book chapters:
- Campbell DJ, Aggarwal A, Esler M, Kaye D. -blockers, angiotensin II, and ACE inhibitors in patients with heart failure. Lancet 2001;358:1609-1610.
- Mackie F, Meyer TW, Campbell DJ. Effect of antihypertensive therapy on intrarenal angiotensin and bradykinin levels in experimental renal insufficiency. Kidney International 2002;61:555-563.
- Zeitz C, Campbell DJ, Horowitz JD. Myocardial uptake and biochemical and hemodynamic effects of ACE inhibitors in humans. Hypertension 2003;41:482-487.
- Dixon B, Santamaria JD, Campbell DJ. Plasminogen activator inhibitor activity is associated with raised lactate levels after cardiac surgery with cardiopulmonary bypass. Critical Care Medicine 2003;31:1053-1059.
- Campbell DJ, Alexiou T, Xiao HD, Fuchs S, McKinley MJ, Corvol P, Bernstein KE. Effects of reduced angiotensin converting enzyme gene expression and angiotensin converting enzyme inhibition on angiotensin and bradykinin peptide levels in mice. Hypertension 2004;43:854-859.
- Xiao HD, Fuchs S, Campbell DJ, Lewis W, Dudley SCJr, Kasi VS, Hoit BD, Keshelava G, Capecchi MR, Bernstein KE. Mice with cardiac restricted angiotensin converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia and sudden death. American Journal of Pathology 2004;165:1019-1032.
- Campbell DJ, Zeitz CJ, Esler MD, Horowitz JD. ACE2 does not play a major role in angiotensin peptide metabolism in the human coronary circulation. Journal of Hypertension 2004;22:1971-1978.
- Campbell DJ, Woodward M, Chalmers JP, Colman SA, Jenkins AJ, Kemp BE, Neal BC, Patel A, MacMahon SW. Prediction of heart failure by amino-terminal-pro-B-type natriuretic peptide and C-reactive protein in subjects with cerebrovascular disease. Hypertension 2005;45:69-74.
- Campbell DJ, Krum H, Esler MD. Losartan increases bradykinin levels in hypertensive humans. Circulation 2005;111:315-320.
- Alexiou T, Boon WM, Denton DA, Di Nicolantonio R, Walker LL, McKinley MJ, Campbell DJ. Angiotensinogen and angiotensin converting enzyme gene copy number and angiotensin and bradykinin peptide levels in mice. Journal of Hypertension 2005;23:945-954.
- Campbell DJ, Woodward M, Chalmers JP, Colman SA, Jenkins AJ, Kemp BE, Neal BC, Patel A, MacMahon SW. Prediction of myocardial infarction by N-terminal-pro-BNP, C-reactive protein and renin in subjects with cerebrovascular disease. (Circulation, in press).
- Campbell DJ. Heart failure: how can we prevent the epidemic? Medical Journal of Australia 2003;179:422-425.
