Research units
Research units
Structural Biology
Proteins are one of the body's most essential building blocks and are the molecular engines that control all functions of the body. X-ray crystallography offers the means to view the...
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Protein Chemistry and Metabolism
Our research is concerned with the control of the body’s energy metabolism via an enzyme called AMP-activated protein kinase (AMPK). This enzyme acts as the body’s fuel gauge, determining its energy...
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Molecular Cardiology
Despite major advances in treatment and prevention, cardiovascular diseases (heart attack, stroke, heart failure) remain major causes of premature death and disability in our community. Our research...
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Immunology and Diabetes
People with type 1 diabetes can’t make insulin, the hormone that regulates the body’s use of glucose. Insulin is produced by beta cells in the pancreas, which are found in small clumps of cells...
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Bone Cell Biology and Disease
While it may seem that our bones are unchanging, the structure is constantly being renewed so it can adapt to changes in diet and activity levels: some cells dissolve old bone and new replacement...
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Stem Cell Regulation
Billions of blood cells are produced in our body each day, due to highly controlled regulation of self-renewal and differentiation processes of blood stem cells. Blood cell production predominantly...
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Haematology and Leukaemia
We study normal blood maturation of the T, B and myeloid lineages. Additionally, we are developing mouse models of abnormal blood maturation such as lymphoma and leukaemia.
Research Overview
The...
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Molecular Genetics
Proper repair of spontaneous and environmentally induced DNA damage is crucial for normal human development and prevention of cancer and premature ageing. The laboratory is interested in molecular...
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Cell Cycle and Cancer
In higher eukaryotes, controlled cell proliferation and differentiation is required for normal growth and development. Deregulation of cell growth pathways leading to unrestrained cell division is...
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Cytoskeleton and Cancer
The actin cytoskeleton plays a very important role in the regulation of many cellular functions.
Research Overview
Understanding the mechanisms influencing the organization of the actin network...
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Pharmacogenomics
Pharmacogenomics is the study of how an individual’s genetic makeup affects the course of disease and responses to medication. Work at SVI combines traditional sciences, such as biochemistry, with...
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Invasion and Metastasis
The Invasion and Metastasis Unit (St Vincent’s Institute and Department of Surgery, Melbourne University) arose in 1997 through the Victorian Breast Cancer Research Consortium (VBCRC), a consortium...
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NRL
The National Serology Reference Laboratory, Australia (NRL™) is committed to helping curb the spread of blood-borne and other infections by assuring the quality and confidence in laboratory results...
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Genome Stability
The Genome Stabiliity Unit is the newest addition to St Vincent’s Institute. Our lab focuses on the mechanisms cells use to protect themselves from cancer-causing mutations.
Research Overview
We...
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