Cytoskeleton and Cancer - Senior Research Staff - Dr Ora Bernard

Dr Ora Bernard

Unit Head

Education and Professional Experience

1966          MSc in Biochemistry and Microbiology, Tel-Aviv University, Israel
1973          PhD in Biochemistry, McGill University, Montreal Canada
1996          Master in Psychoanalytic Studies, Monash University
1967-68     Visiting Scientist, Institute de Recherche sur les maladie du sang, Hopital
                  St. Louis, Paris
1969          Research Assistant, GD Searle Research Laboratories, High-Wycombe, UK
1973          Post Doctoral Fellow, The University of Melbourne, Microbiology
1974-77     Post Doctoral Fellow, Molecular Biology Unit, The Walter and Eliza Institute
1977-79     Member, The Basel Institute for Immunology
1979-81     Senior Research Officer, Molecular Biology Unit, WEHI
1981-84     Research Fellow, Molecular Biology Unit, WEHI
1985          Sabbatical, The Weizmann Institute of Science, Rehovot, Israel
1986-94     Senior Research Fellow, Head, Molecular Neurobiology Laboratory, WEHI
1994-2005 Principal Research Fellow, Head, Molecular Neurobiology Laboratory, WEHI
2006-         Principal Research Fellow, Head, Cytoskeleton and Cancer Laboratory, SVI

Achievements

1967-68     The Minister of Cultural Affairs Fellowship, France
1969-73     Postgraduate Research Fellowship, MRC, Canada
1973-76     Postdoctoral Fellowship of the Canadian MRC
1985          Visiting Scientist Fellowship, The Weizmann Institute, Rehovot, Israel
2001          Visiting Scientist Fellowship, Shanghai Second Medical University, China

Research Interests

Dynamics of the actin cytoskeleton

Selected Publications

  1. Dan C, Kelly A, BERNARD O, Minden A. Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin. J Biol Chem 276:32115-32121, 2001.
  2. Whitfield J, Neame, SJ, Paquet L, BERNARD O, Ham J. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29:629-643, 2001.
  3. Erickson RP and BERNARD O. Studies on Neuronal Death in the Mouse Model of Niemann-Pick C Disease. JNR, 68: 738-774, 2002
  4. Yoshioka K, Foletta V, BERNARD O and Itoh K. A role for LIM kinase in cancer metastasis. Proc Natl Acad Sci USA 100:7247-7252, 2003.
  5. Victoria C. Foletta, Mei Ann Lim, April P. Kelly, Edouard G. Stanley, Mark Shannon, Juliana Soosairajah, Wei He, Supratik Das, Joan Massagu