Life in the Lab

Profile - Helen Thomas - Diabetes

Posted 06th July 2016

Associate Professor Helen Thomas, Associate Director SVI
Head, Immunology and Diabetes Unit
NHMRC Senior Research Fellow
Research interests: My research is focused on preventing pancreatic beta cell destruction to preserve beta cell mass in diabetes. My lab has identified pathways of beta cell death in type 1 and 2 diabetes. We aim to understand how different effector mechanisms participate in diabetes development, and how they can be prevented. In type 1 diabetes, we study the interaction between the immune system and beta cells. We are studying the stress, inflammatory and cell death pathways activated by high glucose concentrations in beta cells in type 2 diabetes, and we are testing the role of these pathways in vivo. Our work is being applied to humans through the transplantation of human islets from organ donors to reverse diabetes in severe cases.
Learn more about Helen here.

Profile - Natalie Sims - Bone Cell Biology and Disease

Posted 06th July 2016

Associate Professor Natalie Sims, Associate Director SVI
Head, Bone Cell Biology and Disease Unit
NHMRC Senior Research Fellow
Research goal: to identify new pathways for treatment of bone disease by studying intercellular communication within the bone microenvironment, particularly the communication between osteoblasts (bone forming cells) and osteoclasts (bone resorbing cells). 
Read more about Natalie here.

Profile - Andrew Deans - Genome Stability

Posted 06th July 2016

Dr Andrew Deans, Head Genome Stability Unit SVI
Victorian Cancer Agency (VCA) Mid Career Fellow
Research interests: Familial breast/ovarian cancer; Fanconi Anaemia; Bloom’s Syndrome; DNA damage signalling and repair; regulation of ubiquitination; roles of DNA damage response proteins during chemotherapy.
Read more about Andrew here.

Profile - Michael Parker - Structural Biology

Posted 26th May 2016

Professor Michael Parker, Deputy Director SVI
Head, Structural Biology Unit and Australian Cancer Research Foundation (ACRF) Rational Drug Discovery Centre
Research interests: Alzheimer's disease, cancer, bacterial and viral infections.
Read more about Michael here.

Why is medical research important ?

Posted 24th November 2015

Research at SVI focuses on diseases that affect many Australian families.

Women in Research 2015

Posted 08th May 2015

Life as a researcher and mother, explained by three of our most senior researchers.

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