Profile - Helen Thomas - Diabetes
Posted 06th July 2016
Associate Professor Helen Thomas, Associate Director SVI
Head, Immunology and Diabetes Unit
NHMRC Senior Research Fellow
Research interests: My research is focused on preventing pancreatic beta cell destruction to preserve beta cell mass in diabetes. My lab has identified pathways of beta cell death in type 1 and 2 diabetes. We aim to understand how different effector mechanisms participate in diabetes development, and how they can be prevented. In type 1 diabetes, we study the interaction between the immune system and beta cells. We are studying the stress, inflammatory and cell death pathways activated by high glucose concentrations in beta cells in type 2 diabetes, and we are testing the role of these pathways in vivo. Our work is being applied to humans through the transplantation of human islets from organ donors to reverse diabetes in severe cases.
Learn more about Helen here.