Cynthia will develop an open-source software tool that can identify and visualise cell clusters, infer cell-to-cell interactions, define the structure of each cell cluster and report the localisation of neighbouring cells. She will also publicly release a simple web-based, ‘click-and-go’ interactive tool for studying the patterns of cells in tissues – to support biologists with no knowledge of programming.
“The software and web-based tools will help biologists fully utilise their data, providing greater information from what is a largely untapped source of novel biological insight,” Cynthia says. “To date, very few tools have been produced to support the spatial analysis of cells in tissues.”
Cynthia’s work opens the way for SVI to develop imaging analysis expertise that can support researchers on the St Vincent’s campus and beyond.