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Dr Jessie Yang

Postdoctoral Researcher, Diabetes & metabolic disease Laboratory

Uncovering new pathways to treat type 2 diabetes

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The Problem

Type 2 diabetes is a massive health burden worldwide that can result in heart attack, stroke, blindness and amputation. Almost one million Australians have type 2 diabetes.

Influenced by genetic and family-related risk factors as well as environmental factors, the exact cause of the disease remains unknown.  

Available treatments for type 2 diabetes do not adequately prevent disease progression – new treatments are therefore urgently needed. 

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The Project

Jessie’s research has identified a new potential means to address defects in the cells that produce insulin (beta cells) – defects that may be a key driver of type 2 diabetes progression.  

“My work has identified a potential set of signalling molecules that can improve beta cell function,” says Jessie. “Inhibition of this pathway can stimulate higher insulin release, improve glucose tolerance, and may result in protective effects against diabetes-related stress on beta cells.” 

The project will take Jessie’s initial findings to the next level, enabling further investigation of the pathway, alongside the development of testing to identify new potential drugs that act upon it. 

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Dr Jessie Yang

Dr Jessie Yang’s research is focused on understanding underlying drivers in the body that lead to metabolic diseases (including diabetes and obesity), and how these processes can be harnessed to identify new treatments. 

Following her PhD at The University of Melbourne, in 2019 Jessie joined SVI’s Diabetes & Metabolic Disease Laboratory to continue her promising research into type 2 diabetes.