Research Unit
Cardiac regeneration
Information
Post-doctoral Research Fellow
Honourary Fellow, University of Melbourne
Email: [email protected] | [email protected]
Professional Experience
2019 Honorary Fellow, University of Melbourne
2018 Post-doctoral Research Officer, SVI
2018 Research Assistant, University of Melbourne
2017 PhD, University of Melbourne
2013 MSc, University of Melbourne
2011 BSc, University of Melbourne
2011 DipLang (French), University of Melbourne
Achievements
2019 National Ataxia Foundation Young Investigator Award
2019 The CASS Foundation Medical Research Grant
2019 St Vincent’s Hospital Research Endowment Fund Grant, St Vincent’s
Hospital
2019 Australasian Society for Stem Cell Research ECR Oral Award
2019 Aikenhead Centre for Medical Discovery Senior Medical Staff Best Poster
Prize
2019 FameLab Victorian Finalist
2016 Alfred Nicholas Fellowship Award, University of Melbourne
2016 F.H Drummond Travel Award, University of Melbourne
2016 Science Abroad Travelling Scholarship, University of Melbourne
2016 University of Melbourne 3-Minute Thesis competition – Grand finalist
2015 University of Melbourne 3-Minute Thesis competition – Grand finalist
2014 Australian Post Graduate Award (APA) for PhD study
2014 Jasper Loftus-Hills Award, University of Melbourne
Research Interests
Stem cell derived organoid models, human induced pluripotent stem cell differentiation, sympathetic neurons, endothelial cells, cardiomyocytes, Friedreich’s ataxia associated cardiomyopathy, stem cell metabolism.
Selected Publications
- Lees, J. G., Gardner, D. K. & Harvey, A. J. (2020). NAD+ induces a bivalent metabolism and maintains pluripotency in human embryonic stem cells. Stem Cells. 2020; 1-15. https://doi.org/10.1002/stem.3152.
- Lees, J. G., Kong, A. M., Chen, Y. C., Sivakumaran, P., Hernández, D., Pébay, A., Harvey, A. J., Gardner, D. K., Lim, S. Y. (2019). Mitochondrial fusion by M1 promotes embryoid body cardiac differentiation of human pluripotent stem cells. Stem Cells International. 2019: 12, Article ID 6380135.
- Lees, J. G., Cliff, T. S., Gammilonghi, A., Ryall, J. G., Dalton, S., Gardner., D. K., Harvey, A. J. (2019). Oxygen regulates human pluripotent stem cell metabolic flux. Stem Cells International, 2019: 17, Article ID 8195614
- Kong, A. M., Yap, K. K., Lim, S. Y., Marre, D., Pébay, A., Gerrand, Y. W., Lees, J. G., Palmer, J. A., Morrison, W. A. and Mitchell, G. M. (2019). Bio-engineering a tissue flap utilizing a porous scaffold incorporating a human induced pluripotent stem cell-derived endothelial cell capillary network connected to a vascular pedicle. Acta biomaterialia, 94, 281-294.
- Lees, J. G., Gardner, D. K. & Harvey, A. J. (2018). Mitochondrial and glycolytic remodeling during nascent neural differentiation of human pluripotent stem cells. Development, 145(20), dev168997.
- Lees, J. G., Gardner, D. K. & Harvey, A. J. (2017). Pluripotent stem cell metabolism and mitochondria: beyond ATP. Stem Cells International, 2017: 17.
- Lees, J. G., Rathjen, J., Sheedy, J. R., Gardner, D. K., & Harvey, A. J. (2015). Distinct profiles of human embryonic stem cell metabolism and mitochondria identified by oxygen. Reproduction, 150(4), 367-382.