My research interests are exploring molecular mechanisms involved in disease development particularly cancer and adipose tissue-associated disorders (obesity, lipoedema, and lymphedema). My recent project is to discover the molecular mechanism involved in lipoedema development. My research work has made a key contribution to the lipoedema field which will lead to the development of therapeutic and diagnostic targets.
Key achievements
2012 CSIRO OCE Fellowship
2011 Stockholm University, Seden Scholarship
2008 NIH Postdoctoral Fellowship, University of Wisconsin-Madison, USA
Selected publications
Musarat Ishaq et al (2022) Key signaling networks are dysregulated in patients with the adipose tissue disorder lipedema. Int J Obes. 46(3):502-514.
Arcucci V, Ishaq Musarat, et al (2021) The microRNA miR-132 is a key regulator of lymphatic vascular remodelling. bioRxiv, 2021.12.22.473780.
N Davydova, NC Harris, S Roufail, S Paquet, Musarat Ishaq, et al (2016) Differential receptor binding and regulatory mechanisms for the lymphangiogenic growth factors vascular endothelial growth factors (VEGF)-C and -D. Journal of Biological Chemistry 291 (53), 27265-27278.
N Xiang, Musarat Ishaq et al (2016) The DEAD-box RNA helicase DDX3 interacts with NF-kB subunit p65 and suppresses p65-mediated transcription. PloS One 11 (10) e0164471.
Musarat Ishaq et al. (2014) Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis. Molecular Biology of the Cell; 25 (1): 1523-1531.
Musarat Ishaq et al. (2013) Effects of atmospheric gas plasmas on cancer cell signaling. International Journal of Cancer; 134 (7): 1517-1528
http://scholar.google.com.au/citations?user=avDxzDQAAAAJ&hl=en