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FAQs

Who can participate?

People aged 10 – 30, who have been diagnosed with type 1 diabetes within the last 100 days, may be eligible to participate. 

Where is the trial being conducted and how long will it last?

This is an Australian-based trial being undertaken over two years at three sites in Melbourne Australia: The Royal Melbourne Hospital, The Royal Children’s Hospital Melbourne and St Vincent’s Hospital Melbourne and at one site in Adelaide Australia – the Women’s and Children’s Hospital.

Why should I participate in this trial?

If the drug helps to preserve a participant’s ability to make insulin, participants may find it easier to control glucose levels and may be able to decrease their insulin doses. Participants will help to advance type 1 diabetes research and may also benefit from the additional monitoring of their diabetes provided by the trial and from close interaction with the research team.

What kind of things will the trial participant have to do?

Participants will be asked to provide details of their medical history and be examined by a trial doctor.

Blood samples will be collected to check for blood cell counts, liver and kidney function, blood glucose levels and other measurements such as immune system genes, called HLA, which play an important role in the development of type 1 diabetes.

During the trial, participants will be asked to undertake meal tests, and have a glucose monitor fitted at times.

In between the trial visits at the hospital, a member of the trial team will contact participants regularly by telephone to enquire about any concerns and to review participant treatment with insulin.

Is there a cost to participate in the BANDIT trial?

No; all medication, tests and medical care required as part of the research project will be provided free of charge. Participants will be reimbursed for any reasonable travel, parking, meals and other expenses associated with the research project visit.

How will the trial work?

There will be two groups in this trial – two thirds of the participants will be given baricitinib (a tablet) and one third of the participants will be given a placebo (a tablet). A placebo looks like the real drug but has no active ingredients. The main reason to have a placebo group is to be sure that any effects that happen are caused by the treatment and not by something else.

How will participant privacy be managed?

All identifying information will be kept confidential.

When the results of this trial are known, they will be made available to participants who ask for them.

Who is leading the BANDIT trial?

The BANDIT trial is being led by St Vincent’s Institute (SVI) in Melbourne Australia, with funding provided by JDRF. 

Who has approved the research project?

The ethical aspects of this research project have been approved by the Human Research Ethics Committee (HREC) of the Royal Melbourne Hospital (Melbourne Health). It will be carried out according to the Australian Government’s National Statement on Ethical Conduct in Human Research (2007).

The trial is registered with the Australian New Zealand Clinical Trial Registry: ACTRN12620000239965.

These questions are included in the BANDIT Trial Information Sheet, which can be saved or downloaded here.

Where can I get more information about the trial?

For more information, please contact:

  • the BANDIT trial coordinator via email at [email protected] or by telephone on 0450 323 962, or

  • Associate Professor John Wentworth via email at [email protected] or by telephone on (03) 9342 7344.  

Alternatively,  you can fill out an enquiry form on this web page: www.svi.edu.au/bandit

Please note that all applications to participate in the BANDIT trial will be assessed, but as we have almost reached our maximum participant capacity, we cannot guarantee your place in the trial. Thank you for your interest and understanding.

Additional information on clinical trials

To find out about other clinical trial opportunities in Australia, please visit:

To find out about other type 1 diabetes clinical trial opportunities happening globally, please visit:

Every clinical trial will have its own specific eligibility guidelines; we recommend you contact their trial managers or clinical trial site personnel for more information.