UP
-
Cancer's achilles heel
Relapse during PARP inhibitor treatment has already been seen in the clinic.Dr Wayne Crismani is working to develop a new set of compounds that act in the same way as PARP inhibitors, but on a different arm of the DNA repair pathway.More
-
Putting the brakes on
The exact chain of events that leads to Alzheimer’s is still unclear.More recently, the finger has also been pointed at immune cells called microglia – cellular scavers tasked with scouring the brain and gobbling up damaged material. More
-
At the heart of it
The relationship between type 2 diabetes and heart disease is complex.Dr Kim Loh has received support from the L.E.W. Carty Charitable Fund and the National Health and Medical Research Council to look at the role that AMPK plays in heart disease.More
-
Digging for clues
About 60% of fragility fractures actually happen in people who have normal scans.Research using human bone samples is required to understand more about how the skeleton works, and how it reacts as a person ages.More
-
Finding a new purpose
"We are planning a clinical trial to test this drug in people with newly diagnosed type 1 diabetes."On average, bringing a new drug to market costs $2-3 billion and takes more than 13 years of intense study and clinical trials.More
