SVI InFocus: A supercharged period of discovery and emerging talent

We are proud to release our Autumn 2025 edition of InFocus. This edition explores how we’re driving groundbreaking discoveries across cancer, diabetes, heart disease, and more, thanks to generous funding and visionary leadership. From major NHMRC grants to philanthropic support through the Discovery Fund and Rising Star Program, this vibrant period of research highlights SVI’s commitment to solving real-world health challenges and nurturing the next generation of scientific leaders. Explore how innovation, generosity, and collaboration are shaping a healthier future.

Supercharged period of discovery: trio win backing

Three SVI researchers have secured over $6.5 million in NHMRC Investigator Grants to tackle key diseases. Dr Sarah Henrikus will investigate DNA repair to better understand and treat cancer and genetic disorders. Associate Professor Davis McCarthy received $2.8 million to develop AI tools for identifying new treatments in cancer and lung diseases. Professor Tom Kay was awarded over $3 million to advance therapies for type 1 diabetes, aiming to preserve insulin production.

Leadership updates and strategic moves

After eight years, Karen Inge steps down as Chair of the SVI Foundation, passing leadership to Jeremy Gobbo KC. Two new board members, Kathryn Fink and Maree Davenport, also join. Meanwhile, SVI prepares to relocate 45 researchers to the new Aikenhead Centre for Medical Discovery (ACMD), a cutting-edge facility focused on interdisciplinary solutions to real-world healthcare issues.

Celebrating the impact of the Discovery Fund

The Discovery Fund, launched to provide critical financial support for researchers, has surpassed its $5 million goal, now standing at over $8 million. More than $2 million has already been distributed since 2021, supporting innovative work in cancer, cardiology, and computational biology. Notable beneficiaries include Associate Professor Elaine Sanij and Professor André La Gerche. At the 2024 Discovery Fund lunch, a record $1 million was allocated for research.

Finger-prick testing pioneer joins SVI

SVI welcomes Professor John Wentworth, pioneer of at-home type 1 diabetes screening, as Senior Clinical Research Fellow. His focus includes early detection and preserving beta cell function through immune therapy. John led the BANDIT trial and heads several national diabetes research programs, further enhancing SVI’s leadership in diabetes research.

Unlocking the secrets to gut health

A new microbiome lab, co-directed by Professors Michael Kamm and Mark Morrison, aims to improve outcomes for people with gut diseases like Crohn’s and Ulcerative Colitis. Leveraging 15 years of data, the lab is undertaking world-first clinical trials and developing new treatments, including faecal microbiota transplants and dietary therapies, in collaboration with St Vincent’s Hospital and the University of Melbourne.

Understanding cardiac arrest vs. heart attack

While often confused, heart attacks and cardiac arrest differ significantly. A heart attack stems from blocked arteries; cardiac arrest is due to electrical failure causing the heart to stop. Both are emergencies. Immediate action—calling emergency services, performing CPR, or using a defibrillator—can save lives.

When Alison met Kate

SVI supporter Alison Hyams funds a Rising Star Fellowship for Dr Kate Firipis, who is developing lab-grown human skin for reconstructive surgery. Her work could replace traditional skin flap techniques, reducing complications and improving recovery. Kate uses stem cell technology to create skin that can regain sensation. Alison was inspired by Kate’s passion and clarity of purpose.

Rising Stars: Empowering the next generation of researchers

Over $225,000 was raised at SVI’s “For the Love of Science” dinner to support Rising Star Awards, which fund early-career researchers with up to $40,000 each. Fellows like Dr Emma van der Westhuizen are already working on diseases like dementia. SVI’s Rising Star Program empowers young scientists through substantial fellowships and funding, fostering innovation in critical health areas.

Ruth and Gus: A legacy of love and giving back

Ruth Leitch, fondly remembered as part of the inseparable duo “Gus and Ruth,” lived a life of adventure, generosity, and love. The couple embraced music, art, and friendship, leaving a mark on those around them. Ruth’s decision to include SVI in her Will supports future medical research. Her legacy is a reminder that planned giving can create lasting impact for generations.

If you’re interested in supporting the future of medical research, please reach out to the SVI Foundation on (03) 9231 3265 or [email protected].